Rui Fu, RNA biologist

Research interests

Post-transcriptional gene expression regulation

Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements.
Fu R, Olsen MT, Webb K, Bennett EJ, Lykke-Andersen J. RNA, 2016. link

PNPT1 release from mitochondria during apoptosis triggers decay of poly(A) RNAs.
Liu X*, Fu R*, Pan Y, Meza-Sosa K, Zhang Z, Lieberman J. Cell, 2018. link

RNA-binding proteins regulate aldosterone homeostasis in human steroidogenic cells.
Fu R*, Wellman K*, Baldwin A, Rege J, Walters K, Hirsekorn A, Riemondy K, Rainey W, Mukherjee N. RNA, 2021. link

Dynamic RNA Regulation in the Brain Underlies Physiological Plasticity in a Hibernating Mammal.
Fu R*, Gillen A*, Grabek K, Riemondy K, Epperson E, Bustamant C, Hesselberth J, Martin S. Frontiers in Physiology, 2021. link

Liver transcriptome dynamics during hibernation are shaped by a shifting balance between transcription and RNA stability.
Gillen A*, Fu R*, Riemondy K*, Jager J, Fang B, Lazar M, Martin S. Frontiers in Physiology, 2021. link

Transcriptomic Response Dynamics of Human Primary and Immortalized Adrenocortical Cells to Steroidogenic Stimuli.
Wellman K*, Fu R*, Baldwin A, Rege J, Murphy E, Rainey W, Mukherjee N. Cells, 2021. link

Single cell RNA sequencing analysis and software development

clustifyr: an R package for automated single-cell RNA sequencing cluster classification.
Fu R, Gillen A, Sheridan R, Tian C, Daya M, Hao Y, Hesselberth J, Riemondy K. F1000Research, 2020. link

Cell-level metadata are indispensable for documenting single-cell sequencing datasets.
Puntambekar S, Hesselberth J, Riemondy K*, Fu R*. PLoS Biology, 2021. link

Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Acute Myeloid Leukemia Patients.
Pei S, Pollyea D, Gustafson A, Stevens B, Minhajuddin M, Fu R, Riemondy K, Gillen A, Sheridan R, Kim J, Costello J, Amaya M, Inguva A, Winters A, Ye H, Krug A, Jones C, Adane B, Khan N, Ponder J, Schowinsky J, Abbott D, Hammes A, Myers J, Ashton J, Nemkov T, D’Alessandro A, Gutman J, Fesik S, Ramsey H, Savona M, Smith C, Jordan C. Cancer Discovery, 2019. link

Molecular tracking devices quantify antigen distribution and archiving in the murine lymph node.
Walsh S, Sheridan R, Doan T, Lucas E, Ware B, Fu R, Burchill M, Hesselberth J, Tamburini B. eLife, 2021. link

Publication List ORCID iD iconCU Profile

Publons Reviews